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Volume 17, Issue 2 , October 2002, Pages 956-966

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doi:10.1016/S1053-8119(02)91154-7    How to Cite or Link Using DOI (Opens New Window)  
Copyright © 2002 Elsevier Science (USA). All rights reserved.

Regular Article

Bach Speaks: A Cortical “Language-Network” Serves the Processing of Music

Stefan Koelschb, a, 1, Thomas C. Guntera, D. Yves v. Cramona, Stefan Zysseta, Gabriele Lohmanna and Angela D. Friedericia

a Max Planck Institute of Cognitive Neuroscience, Leipzig, Germany
b Department of Neurology, Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts, 02215

Received 30 October 2000.  Available online 5 October 2002.


Abstract

The aim of the present study was the investigation of neural correlates of music processing with fMRI. Chord sequences were presented to the participants, infrequently containing unexpected musical events. These events activated the areas of Broca and Wernicke, the superior temporal sulcus, Heschl's gyrus, both planum polare and planum temporale, as well as the anterior superior insular cortices. Some of these brain structures have previously been shown to be involved in music processing, but the cortical network comprising all these structures has up to now been thought to be domain-specific for language processing. To what extent this network might also be activated by the processing of non-linguistic information has remained unknown. The present fMRI-data reveal that the human brain employs this neuronal network also for the processing of musical information, suggesting that the cortical network known to support language processing is less domain-specific than previously believed.

Author Keywords: brain; music; language; fMRI; Broca; Wernicke; superior temporal sulcus; superior temporal gyrus; insular cortex; modulation


References

1. G. Aguirre, E. Zarahn and M. d'Esposito , Empirical analyses of BOLD fMRI statistics. II. Spatially smoothed data collected under null-hypothesis and experimental conditions. NeuroImage 5 (1997), pp. 199–212. Abstract | Abstract + References | PDF (326 K)

2. C. Alain, D. L. Woods and R. T. Knight , A distributed cortical network for auditory sensory memory in humans. Brain Res. 812 (1998), pp. 23–37. SummaryPlus | Full Text + Links | PDF (4366 K)

3. K. Alho, M. Tervaniemi, M. Huotilainen, J. Lavikainen, H. Tiitinen, R. Ilmoniemi, J. Knuutila and R. Näätänen , Processing of complex sounds in the human auditory cortex as revealed by magnetic brain responses. PsPh 33 (1996), pp. 369–375. Abstract-EMBASE | Abstract-MEDLINE  

4. P. Auzou, F. Eustache, P. Etevenon, H. Platel, P. Rioux, J. Lambert, B. Lechevalier, E. Zarifian and J. Baron , Topographic EEG activations during timbre and pitch discrimination tasks using musical sounds. Neuropsychologia 33 (1995), pp. 25–37. Abstract | Abstract + References | PDF (861 K)

5. P. Bellin, R. Zatorre, P. Lafaille, P. Ahad and B. Pike , Voice-selective areas in human auditory cortex. Nature 403 (2000), pp. 309–312.

6. J. Bharucha and C. Krumhansl , The representation of harmonic structure in music: Hierarchies of stability as a function of context. Cognition 13 (1983), pp. 63–102. Abstract | Abstract + References | PDF (3641 K)

7. J. Bharucha and K. Stoeckig , Reaction time and musical expectancy: Priming of chords. J. Exp. Psychol. Hum. Percept. Perform. 12 (1986), pp. 403–410. Abstract-MEDLINE   | Full Text via CrossRef

8. E. Bigand, F. Madurell, B. Tillmann and M. Pineau , Effect of Global Structure and Temporal Organization on Chord Processing. J. Exp. Psychol. Hum. Percept. Perform. 25 (1999), pp. 184–197. Abstract | Full Text via CrossRef

9. E. Bigand and M. Pineau , Global context effects on musical expectancy. Percept. Psychophys. 59 (1997), pp. 1098–1107. Abstract-MEDLINE  

10. J. Binder, S. Rao, T. Hammeke, F. Yetkin, A. Jesmanowicz, P. Bandettini, E. Wong, L. Estkowski, M. Goldstein, V. Haughton and J. Hyde , Functional magnetic-resonance-imaging of human auditory-cortex. Ann. Neurol. 35 (1994), pp. 662–672. Abstract-MEDLINE | Abstract-EMBASE | Abstract-Elsevier BIOBASE   | Full Text via CrossRef

11. A. Blood, R. Zatorre, P. Bermudez and A. Evans , Emotional responses to pleasant and unpleasant music correlate with activity in paralimbic brain regions. Nature Neurosci. 2 (1999), pp. 382–387. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

12. V. Bosch , Statistical analysis of multi-subject fmri data: The assessment of focal activations. J. Magn. Reson. Imag. 11 (2000), pp. 61–64. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

13. A. Chan, Y. Ho and M. Cheung , Music training improves verbal memory. Nature 396 (1998), p. 128. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

14. G. Crummer, J. P. Walton, J. W. Wayman and E. C. Hantz , Neural processing of musical timbre by musicians, nonmusicians, and musicians possessing absolute pitch. J. Acoust. Soc. Am. 95 (1994), pp. 2720–2727. Abstract-MEDLINE | Abstract-INSPEC | Abstract-EMBASE   | Full Text via CrossRef

15. M. Dapretto and S. Bookheimer , Form and content: dissociating syntax and semantics in sentence comprehension. Neuron 24 (1999), pp. 427–432. SummaryPlus | Full Text + Links | PDF (192 K)

16. S. Douglas and P. Willatts , The relationship between musical ability and literacy skills. J. Res. Read. 17 (1994), pp. 99–107. Full Text via CrossRef

17. A. Fernald , Intonation and communicative intent in mothers' speech to infants: Is the melody the message?. Child Dev. 60 (1989), pp. 1497–1510. Abstract-MEDLINE   | Full Text via CrossRef

18. A. D. Friederici Language Comprehension: A Biological Perspective, Springer (1998).

19. A. D. Friederici, M. Meyer and D. Y. v.Cramon , Auditory language comprehension: An event-related fMRI study on the processing of syntactic and lexical information. Brain Lang. 74 (2000a), pp. 289–300. Abstract | Abstract + References | PDF (189 K)

20. A. D. Friederici, E. Pfeifer and A. Hahne , Event-related brain potentials during natural speech processing: Effects of semantic, morphological and syntactic violations. Cogn. Brain Res. 1 (1993), pp. 183–192. Abstract | Abstract + References | PDF (1146 K)

21. A. D. Friederici, Y. Wang, C. Herrmann, B. Maess and U. Oertel , Localisation of early syntactic processes in frontal and temporal cortical areas: A MEG study. Hum. Brain Mapp. 11 (2000b), pp. 1–11. Abstract-MEDLINE | Abstract-Elsevier BIOBASE | Abstract-EMBASE   | Full Text via CrossRef

22. K. Friston , Statistical parametric maps in functional imaging: A general linear approach. Hum. Brain Mapp. 2 (1994), pp. 189–210. Full Text via CrossRef

23. M. Giard, F. Perrin and J. Pernier , Brain generators implicated in processing of auditory stimulus deviance. A topographic ERP study. Psychophysiology 27 (1990), pp. 627–640. Abstract-MEDLINE | Abstract-EMBASE  

24. M. Grossman, B. Shapiro and H. Gardner , Dissociable musical processing strategies after localized brain damage. Neuropsychologia 19 (1981), pp. 425–433. Abstract | Abstract + References | PDF (679 K)

25. A. Hahne and A. D. Friederici , Electrophysiological evidence for two steps in syntactic analysis: Early automatic and late controlled processes. J. Cogn. Neurosci. 11 (1999), pp. 194–205. Abstract-Elsevier BIOBASE | Abstract-EMBASE | Abstract-MEDLINE   | Full Text via CrossRef

26. P. Hindemith Unterweisung im Tonsatz, 1. Theoretischer Teil, Schott, Mainz (1940).

27. A. P. Holmes and K. J. Friston , Generalisability, random effects & population inference. NeuroImage 7 (1998), p. 754.

28. S. Hsiao, D. O'Shaughnessy and K. Johnson , Effects of Selective Attention on Spatial Form Processing in Monkey Primary and Secondary Somatosensory Cortex. J. Neurophysiol. 70 (1993), pp. 444–447. Abstract-MEDLINE | Abstract-EMBASE  

29. L. Jäncke, S. Mirzazade and N. Shah , Attantion modulates activity in the primary and the secondary auditory cortex: A functional magnetic resonance imaging study in human subjects. Neurosci. Lett. 266 (1999), pp. 125–128. SummaryPlus | Full Text + Links | PDF (163 K)

30. S. Jones, O. Longe and M. Vaz Pato , Auditory evoked potentials to abrupt pitch and timbre change of complex tones: electrophysiological evidence of “streaming”?. Electroencephalog. Clin. Neurophysiol. 108 (1998), pp. 131–142. Abstract | PDF (885 K)

31. P. Jusczyk, K. Hirsh-Pasek, D. Kemler-Nelson, L. Kennedy, A. Woodward and J. Piwoz , Perception of acoustic correlates of major phrasal units by young infants. Cogn. Psychol. 24 (1992), pp. 252–293. Abstract | PDF (2941 K)

32. P. W. Jusczyk and C. L. Krumhansl , Pitch and rhythmic patterns affecting infants' sensitivity to musical phrase structure. J. Exp. Psychol. Human Perception & Performance 19 (1993), pp. 627–640. Abstract | Full Text via CrossRef

33. M. Just, P. Carpenter, T. Keller, W. Eddy and K. Thulborn , Brain activation modulated by sentence comprehension. Science 274 (1996), pp. 114–116. Abstract-MEDLINE | Abstract-Elsevier BIOBASE   | Full Text via CrossRef

34. S. Koelsch, T. Gunter, A. D. Friederici and E. Schröger , Brain indices of music processing: “Non-musicians” are musical. J. Cogn. Neurosci. 12 (2000a), pp. 520–541. Abstract-EMBASE | Abstract-MEDLINE | Abstract-Elsevier BIOBASE | Abstract-INSPEC   | Full Text via CrossRef

35. S. Koelsch, T. Gunter, E. Schröger, M. Tervaniemi, D. Sammler and A. D. Friederici , Differentiating ERAN and MMN: An ERP-study. NeuroReport 12 (2001), pp. 1385–1389. Abstract-MEDLINE | Abstract-Elsevier BIOBASE | Abstract-EMBASE   | Full Text via CrossRef

36. S. Koelsch, B. Maess and A. D. Friederici , Musical syntax is processed in the area of Broca: an MEG study. Neuroimage 11 (2000b), p. 56.

37. Koelsch, S, Schmidt, B, and, Kansok, J. Influences of musical expertise on the ERAN: An ERP-study, Psychophysiology, in press.

38. S. Koelsch, E. Schröger and T. Gunter , Music Matters: Preattentive musicality of the human brain. Psychophysiology 39 (2002), pp. 1–11.

39. C. Krumhansl and E. Kessler , Tracing the dynamic changes in perceived tonal organization in a spatial representation of musical keys. Psychol. Rev. 89 (1982), pp. 334–368. Abstract-MEDLINE   | Full Text via CrossRef

40. C. L. Krumhansl and P. W. Jusczyk , Infants' perception of phrase structure in music. Psychological Science 1 (1990), pp. 70–73. Full Text via CrossRef

41. C. Liegeois-Chauvel, L. Peretz, M. Babaie, V. Laguitton and P. Chauvel , Contribution of different cortical areas in the temporal lobes to music processing. Brain 121 (1998), pp. 1853–1867. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

42. Lohmann, G, Müller, K, Bosch, V, Mentzel, H, Hessler, S, Chen, L, and, v.Cramon, D. Y. in press, Lipsia—A new software system for the evaluation of functional magnet resonance images of the human brain, Comput. Med. Imag. Graphics. See also at, http://www.cns.mpg.de/lipsia.

43. B. Maess, S. Koelsch, T. Gunter and A. D. Friederici , “Musical Syntax” is processed in the Broca's area: An MEG-study. Nature Neurosci. 4 (2001), pp. 540–545. Abstract-EMBASE | Abstract-MEDLINE  

44. J. Mayer, G. Dogil, H. Ackermann, M. Erb, W. Grodd, H. Haider, A. Riecker and D. Wildgruber , Prosody in speech production. NeuroImage 9 (1999), p. S1065.

45. B. Mazoyer, N. Tzourio, V. Frak, A. Syrota, N. Murayama, O. Levrier, G. Salamon, S. Dehaene, L. Cohen and J. Mehler , The cortical representation of speech. J. Cogn. Neurosci. 5 (1993), pp. 467–479. Abstract-EMBASE  

46. A. Mazzucchi, C. Marchini, R. Budai and M. Parma , A case of receptive amusia with prominent timbre perception defect. J. Neurol. Neurosurg. Psychiatry 45 (1982), pp. 644–647. Abstract-EMBASE | Abstract-MEDLINE  

47. M. Meyer, K. Alter, A. D. Friederici and D. Y. v.Cramon , Different hemodynamic responses to sentence-level syntactic and prosodic processing. NeuroImage 11 (2000a), p. S281. Abstract | PDF (115 K)

48. M. Meyer, A. D. Friederici and D. Y. v.Cramon , Neurocognition of auditory sentence comprehension: Event related fMRI reveals sensitivity to syntactic violations and task demands. Cogn. Brain Res. 9 (2000b), pp. 19–33. SummaryPlus | Full Text + Links | PDF (2102 K)

49. B. Milner , Laterality effects in audition. In: V. Mountcastle, Editor, Interhemisphere Relations and Cerebral Dominance, J. Hopkins Press, Baltimore (1962), pp. 177–194.

50. C. Mummery, J. Ashburner, S. Scott and R. Wise , Functional neuroimaging of speech perception in six normal and two aphasic subjects. J. Acoust. Soc. Am. 106 (1999), pp. 449–457. Abstract-INSPEC | Abstract-MEDLINE | Abstract-Elsevier BIOBASE | Abstract-EMBASE   | OJPS full text | Full Text via CrossRef

51. B. Opitz, A. Mecklinger, D. Y. von Cramon and F. Kruggel , Combining electrophysiological and hemodynamic measures of the auditory oddball. Psychophysiology 36 (1999), pp. 142–147. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

52. H. PapouImageek , Musicality in infancy research. In: J. Sloboda and I. Deliege, Editors, Musical Beginnings, Oxford Univ. Press, Oxford (1996).

53. A. D. Patel, E. Gibson, J. Ratner, M. Besson and P. Holcomb , Processing syntactic relations in language and music: An event-related potential study. J. Cogn. Neurosci. 10 (1998), pp. 717–733. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

54. I. Peretz , Processing of local and global musical information by unilateral brain-damaged patients. Brain 113 (1990), pp. 1185–1205. Abstract-MEDLINE | Abstract-EMBASE  

55. I. Peretz, R. Kolinsky, M. Tramo and R. Labrecque , Functional dissociations following bilateral lesions of auditory cortex. Brain 117 (1994), pp. 1283–1301. Abstract-MEDLINE | Abstract-EMBASE | Abstract-Elsevier BIOBASE  

56. H. Platel, C. Price, J. Baron, R. Wise, J. Lambert, R. Frackowiak, B. Lechevalier and F. Eustache , The structural components of music perception, A functional anatomical study. Brain 120 (1997), pp. 229–243. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

57. D. Pöppel , A Critical Review of PET Studies of Phonological Processing. Brain Lang. 55 (1996), pp. 317–351.

58. D. Raffmann Language, Music, and Mind, MIT Press, Cambridge (1993).

59. P. Roland , Cortical regulation of selective attention in man. A regional cerebral blood flow study. J. Neurophysiol. 48 (1982), pp. 1059–1077.

60. S. Samson and R. Zatorre , Melodic and harmonic discrimination following unilateral cerebral excision. Brain Cogn. 7 (1988), pp. 348–360. SummaryPlus | Full Text + Links | PDF (840 K)

61. S. Samson and R. Zatorre , Contribution of the right temporal lobe to musical timbre discrimination. Neuropsychologia 32 (1993), pp. 231–240.

62. M. Schlosser, N. Aoyagi, R. Fulbright, J. Gore and G. McCarthy , Functional MRI studies of auditory comprehension. Hum. Brain Mapp. 6 (1998), pp. 1–13. Abstract-MEDLINE | Abstract-EMBASE   | Full Text via CrossRef

63. A. Schönberg Structural Functions of Harmony, Norton, rev. edition, New York (1969).

64. B. Shapiro, M. Grossman and H. Gardner , Selective processing deficits in brain damaged populations. Neuropsychologia 19 (1981), pp. 161–169. Abstract | Abstract + References | PDF (787 K)

65. B. Shaywitz, S. Shaywitz, K. Pugh, R. Constable, P. Skudlarski, R. Fulbright, R. Bronen, J. Fletcher, D. Shankweiler, L. Katz and J. Gore , Sex differences in the functional organization of the brain for language. Nature 373 (1995), pp. 607–609. Abstract-EMBASE | Abstract-MEDLINE | Abstract-Elsevier BIOBASE   | Full Text via CrossRef

66. J. Swain Musical Languages, Norton (1997).

67. J. Talairach and P. Tournoux Co-Planar Stereotaxic Atlas of the Human Brain. 3-Dimensional Proportional System: An Approach to Cerebral Imaging, Thieme, Stuttgart (1988).

68. M. Tervaniemi, S. Medvedev, K. Alho, S. Pakhomov, M. Roudas, T. v.Zuijen and R. Näätänen , Lateralized automatic auditory processing of phonetic versus musical information: A PET study. Hum. Brain Mapp. 10 (2000), pp. 74–79. Abstract-Elsevier BIOBASE | Abstract-EMBASE | Abstract-MEDLINE   | Full Text via CrossRef

69. M. Tervaniemi, I. Winkler and R. Näatänen , Pre-attentive categorization of sounds by timbre as revealed by event-related potentials. Neuroreport 8 (1997), pp. 2571–2574. Abstract-MEDLINE | Abstract-EMBASE  

70. B. Tillmann, J. Bharucha and E. Bigand , Implicit learning of tonality: A self-organized approach. Psychol. Rev. 107 (2000), pp. 885–913. Abstract | Full Text via CrossRef

71. B. Tillmann, E. Bigand and M. Pineau , Effects of global and local contexts on harmonic expectancy. Music Percept. 16 (1998), pp. 99–117.

72. P. Toiviainen, M. Tervaniemi, J. Louhivuori, M. Saher, M. Huotilainen and R. Näätänen , Timbre similarity: Convergence of neural, behavioral, and computational approaches. Music Percept. 16 (1998), pp. 223–241.

73. L. Trainor and S. Trehub , A comparison of infants' and adults' sensitivity to western musical structure. JEPP 18 (1992), pp. 394–402. Abstract | Full Text via CrossRef

74. S. Trehub, G. Schellenberg and D. Hill , The origins of music: Perception and cognition: A developmental perspective. In: N. L. Wallin, B. Merker and S. Brown, Editors, The Origins of Music, MIT Press, Cambridge (2000).

75. A. Troyer, M. Moscovitch, G. Winocur, M. Alexander and D. Stuss , Clustering and switching on verbal fluency: The effects of focal frontal- and temporal-lobe lesions. Neuropsychologia 36 (1998), pp. 499–504. SummaryPlus | Full Text + Links | PDF (189 K)

76. K. Worsley and K. Friston , Analysis of fMRI time-series revisited—Again. NeuroImage 2 (1995), pp. 359–365.

77. E. Zarahn, G. Aguirre and M. D'Esposito , Empirical analyses of BOLD fMRI statistics. NeuroImage 5 (1997), pp. 179–197. Abstract | Abstract + References | PDF (426 K)

78. R. Zatorre , Musical perception and cerebral function: a critical review. Music Percep. 2 (1984), pp. 196–221.

79. R. Zatorre , Discrimination and recognition of tonal melodies after unilateral cerebral excisions. Neuropsychologia 23 (1985), pp. 31–41. Abstract | Abstract + References | PDF (988 K)

80. R. Zatorre, A. Evans and E. Meyer , Neural mechanisms underlying melodic perception and memory for pitch. J. Neurosci. 14 (1994), pp. 1908–1919. Abstract-Elsevier BIOBASE | Abstract-EMBASE | Abstract-MEDLINE  

81. R. Zatorre, A. Evans, E. Meyer and A. Gjedde , Lateralization of phonetic and pitch discrimination in speech processing. Science 256 (1992), pp. 846–849. Abstract-MEDLINE | Abstract-INSPEC | Abstract-EMBASE  

82. R. Zatorre and S. Samson , Role of the right temporal neocortex in retention of pitch in auditory short-term memory. Brain 114 (1991), pp. 2403–2417. Abstract-EMBASE | Abstract-MEDLINE  


1 To whom correspondence and reprint requests should be addressed. Fax: 617-667-8695. E-mail: mail@stefan-koelsch.de.



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Volume 17, Issue 2 , October 2002, Pages 956-966


 
 
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